Module 05 — Bad Blood

Target Phenomenon

Why are some people more vulnerable to Duchenne Muscular Dystrophy (DMD)? X-linked inheritance.

NGSS Standards

• HS-LS3-2 — Make and defend a claim based on evidence that inheritable genetic variations may result from new genetic combinations through meiosis, viable errors occurring during replication, and/or mutations caused by environmental factors. (Heredity patterns)
• HS-LS3-3 — Apply concepts of statistics and probability to explain the variation and distribution of expressed traits in a population. (Chromosomal inheritance)
• HS-LS1-1 — Construct an explanation based on evidence for how the structure of DNA determines the structure of proteins which carry out the essential functions of life through systems of specialized cells. (DNA → protein)

Lesson Breakdown

Lesson	Title	Type
L01	[TBD]	Launch
L02	[TBD]	Explore
L03	[TBD]	Explore
L04	[TBD]	Explain
L05	[TBD]	Elaborate
L06	[TBD]	Evaluate

Total: 6 lessons

Recommended Prior Module

M04 — Copy-Paste-Gone-Wrong (Cell Division)

Notes

Retooled from legacy DMD unit. Punnett squares, pedigrees, sex-linked traits. Human-centered, high empathy stakes.